Tapering glucocorticoids in rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
Glucocorticoids in early rheumatoid arthritis.
This series of articles facilitated by the Australian Cochrane Musculoskeletal Group (CMSG), aims to place the findings of recent Cochrane musculoskeletal reviews in a context immediately relevant to general practitioners. This article considers treating patients in the first 2 years of rheumatoid arthritis with low dose of oral corticosteroids.
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Use of glucocorticoids (GC) began more than 50 years ago for the treatment of rheumatoid arthritis (RA). However, up until a decade ago, its potential role as a disease modifying anti-rheumatic drug (DMARD) and its capacity to prevent radiologic damage had not been proposed. Some initial studies indicated a disease modifying drug, but in the following years, probably due to questions regarding ...
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It is evident that the morning symptoms of rheumatoid arthritis (RA) are linked to the circadian abnormal increase in night inflammation, favoured by inadequate cortisol secretion under conditions of active disease. Therefore, exogenous glucocorticoid treatment is recommended in RA at low doses since it may partially act like a 'replacement therapy'. The prevention/treatment of the night upregu...
متن کاملBiological tapering and sonographic flare in rheumatoid arthritis
This study aimed to evaluate the risk of ultrasound-detected synovitis after antitumor necrosis factor (TNF) tapering in patients with rheumatoid arthritis. We recruited patients with rheumatoid arthritis who accepted TNF tapering. Gray-scale synovitis and power Doppler score in bilateral wrists at the dorsal radiolunate joint were evaluated. We defined a sum of bilateral wrist scores of ≥2 as ...
متن کاملKey words: glucocorticoids, rheumatoid arthritis, EULAR recommendations
Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands. Please address correspondence to: Simone L. Gorter, MD, PhD, Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, P. Debyelaan 25, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands. E-mail: [email protected] Received and accept...
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ژورنال
عنوان ژورنال: The Lancet
سال: 2020
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(20)30761-3